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The influence of pharmacological substances from the SYSADOA group on knee osteoarthritis.
Pavlová, Lenka ; Kubový, Petr (advisor) ; Jelen, Karel (referee)
Title: The influence of pharmacological substances from the SYSADOA group on knee osteoarthritis. Objectives: The aim of this work is to determine the effect of three - month usage of pharmacological substances from the SYSADOA group on the subjective perception of the difficulties associated with the knee osteoarthritis and on the reological changes in the joint. Methods: In collaboration with rehabilitation and orthopedic centres 18 probands with knee osteoarthritis in the second degree were obtained. These probands were divided into two groups - the experimetal group (including those who have taken Proenzi 3 plus) and the control group (including those who have taken placebo). With all the pacients the input clinical examination and the medical history were done. Probands had been using these preparations for twelve weeks. After this time, the changes in the subjective perception using the WOMAC test and reological changes in the joint were evaluated, using a special knee rheometer. Results: The results of objectively measured parameters clearly proved that the Proenzi 3 plus has a positive effect on the rheological properties of the knee osteoarthritis. The experimental group had a statistically significant improvement in both of these parameters, as opposed to the control group. Concerning...
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Evaluation of surgical treatment of hip joint with diagnosis of femoroacetabular impingement syndrom.
Zahradník, Petr ; Otáhal, Jakub (advisor) ; Chládek, Petr (referee)
Title: The evaluation of surgical treatment of the hip in the diagnosis of femor- acetabular impingement syndrome. Objectives: The main objective of this work is to evaluate the effect of the surgery of the hip in diagnosis of femor-acetabular hip impingement. Methods: In our work we have cooperated with 103 patients who have been operated on hip with the diagnosis of femor-acetabular hip impingement (FAI). We used standardized questionnaires of WOMAC and NAHS, which assesses functional self- care, limitations in motion and painfulness. Patients completed questionnaires twice. For the first time before surgery and second time at least one year after the surgery. The specimens of questionnaire are attached in the Annex. Results: We found out that postoperative condition is significantly different from the preoperative state in terms of improved self-care, increased range of motion and reduction of painfulness. Keywords: Femor-acetabular impingement, hip surgery, WOMAC, NAHS
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Economic evaluation of surgery compared with pharmacological treatment for patients diagnosed with gonarthrosis
Hájková, Kateřina ; Lešetický, Ondřej (advisor)
The main purpose of my diploma thesis is the application of economic evaluation principles; costs quantification and the consequences quantification of two different approaches in the gonarthrosis therapy from the perspective of Health Insurance Company and from the perspective of the patient; furthermore the evaluation of the effectiveness and utility ratio and the final determination for more convenient option. Considered alternatives are the hyaluronic acid injection and the total knee arthroplasty realization. Effects for the expenditures at cost-effectiveness analysis are measured by WOMAC Index. Effects for the expenditures at cost-utility analysis are measured by HUI2 score system. The research includes two sections: (1) the case study of two patients and (2) the clinical trials and nationwide Health Insurance Company´s data analysis. Particularly because of the brief observation time period, the pharmacotherapy is quantified as a more convenient alternative.
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The influence of pharmacological substances from the SYSADOA group on knee osteoarthritis.
Pavlová, Lenka ; Kubový, Petr (advisor) ; Jelen, Karel (referee)
Title: The influence of pharmacological substances from the SYSADOA group on knee osteoarthritis. Objectives: The aim of this work is to determine the effect of three - month usage of pharmacological substances from the SYSADOA group on the subjective perception of the difficulties associated with the knee osteoarthritis and on the reological changes in the joint. Methods: In collaboration with rehabilitation and orthopedic centres 18 probands with knee osteoarthritis in the second degree were obtained. These probands were divided into two groups - the experimetal group (including those who have taken Proenzi 3 plus) and the control group (including those who have taken placebo). With all the pacients the input clinical examination and the medical history were done. Probands had been using these preparations for twelve weeks. After this time, the changes in the subjective perception using the WOMAC test and reological changes in the joint were evaluated, using a special knee rheometer. Results: The results of objectively measured parameters clearly proved that the Proenzi 3 plus has a positive effect on the rheological properties of the knee osteoarthritis. The experimental group had a statistically significant improvement in both of these parameters, as opposed to the control group. Concerning...
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Influence of drugs from the group SYSASOA for knee osteoarthrosis
Milerová, Klára ; Kubový, Petr (advisor) ; Lopot, František (referee)
Tittle:Influence of drugs from the group SYSADOA for knee osteoarthrosis Objectives:The aim of the thesis is to evaluate the effect of three months use of drugs from the group SASADOA on subjective perception of the difficulties associated with knee osteoarthritis and to determine the intensity of gonarthrosis progression in connection with knee cartilage width. Methods:For the study18 probands were obtained from rehabilitation and orthopedic institutions in Prague. The criterion for recruitmen t was knee joint osteoarthrosis of II. degree. For all participants there was conducted input kinesiology analysis and clinical examination, patient's medical history and filled in WOMAC questionnaire. All participants were sent for an X-ray of the knee. Group of probands was randomly divided into two groups. An experimental group was taking Proenzi 3 plus, a control group was taking placebo. Both groups were taking medications for 12 weeks. After this time the probands arrived to check- up and second filling in of the WOMAC questionnaire. The experimental group that had been taking Proenzi 3 plus received placebo for additional 12 weeks, the control group received Proenzi 3 Plus. After finishing preparations all probands were invited to the last visit where they underwent follow-up examination, the third...
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Evaluation of surgical treatment of hip joint with diagnosis of femoroacetabular impingement syndrom.
Zahradník, Petr ; Otáhal, Jakub (advisor) ; Chládek, Petr (referee)
Title: The evaluation of surgical treatment of the hip in the diagnosis of femor- acetabular impingement syndrome. Objectives: The main objective of this work is to evaluate the effect of the surgery of the hip in diagnosis of femor-acetabular hip impingement. Methods: In our work we have cooperated with 103 patients who have been operated on hip with the diagnosis of femor-acetabular hip impingement (FAI). We used standardized questionnaires of WOMAC and NAHS, which assesses functional self- care, limitations in motion and painfulness. Patients completed questionnaires twice. For the first time before surgery and second time at least one year after the surgery. The specimens of questionnaire are attached in the Annex. Results: We found out that postoperative condition is significantly different from the preoperative state in terms of improved self-care, increased range of motion and reduction of painfulness. Keywords: Femor-acetabular impingement, hip surgery, WOMAC, NAHS
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